Characterization of SPAD Array for Multifocal High-Content Screening Applications
نویسندگان
چکیده
منابع مشابه
Characterization of SPAD Array for Multifocal High-Content Screening Applications
Current instruments used to detect specific protein-protein interactions in live cells for applications in high-content screening (HCS) are limited by the time required to measure the lifetime. Here, a 32 × 1 single-photon avalanche diode (SPAD) array was explored as a detector for fluorescence lifetime imaging (FLIM) in HCS. Device parameters and characterization results were interpreted in th...
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Over the last decade, imaging as a detection mode for cell based assays has opened a new world of opportunities to measure "phenotypic endpoints" in both current and developing biological models. These "high content" methods combine multiple measurements of cell physiology, whether it comes from sub-cellular compartments, multicellular structures, or model organisms. The resulting multifaceted ...
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ژورنال
عنوان ژورنال: Photonics
سال: 2016
ISSN: 2304-6732
DOI: 10.3390/photonics3040056